Friday, March 7th, 2014
11:00am - 12:00pm, in Science 2-065

Leonid Chindelevitch

Harvard School of Public Health

Adventures in Modeling Tuberculosis

Abstract: In this talk I will describe my work on three aspects of tuberculosis. On the molecular level, I will present an algorithm called MetaMerge for reconciling two metabolic network reconstructions of the same organism, with application to M. tuberculosis. I will also describe my toolbox, MONGOOSE, for metabolic network analysis, motivated by tuberculosis but later extended to other organisms. I will finish by describing my recent algorithm, MixTB, on interpreting genetic information from tuberculosis strains to detect mixed infection patterns.